I''m sure Autodesk, Virtualbox, Google Earth, Mathematica, VLC, Transmission, Scribus, Skype, etc, etc would be very interested to hear how unviable they are.
Native apps, be they desktop or mobile, still very much have their place. The iPhone is irrefutable proof of this. Right in the middle of the golden age of the web, Apple has built a ground breaking native app platform that has taken the world by storm. So much so that even web apps like Google+ and Facebook find themselves in an arms race to provide the best native clients.
Please provide some proof when making such extraordinary remarks. Given their requirements, these companies would have to be insane to try to build their apps with web technologies. Are you really suggesting that they do CAD and VOIP using JavaScript?!