Big cities are big enough that you can have vastly different ideas of what it means to "live in New York" or "live in LA" - I had friends in both who would say they lived there, but were a minimum an hour from the central business district.
I gave up answering where I lived years ago, now I just reply with the name of the nearest international airport; people are much more likely to know where LA is than any of the hundreds of smaller cities in and around its metro area.