I meant hardware caches like L1, L2, and L3 on the CPU.
SQLite is used in some HPC work.
ISO-8601 datetime strings can easily wreck your L1 cache. Instead of filling an eighth of the cache with a 64-bit value, you wind up filling almost half with a 27-character-long string.
This runs on python and works with several backends including SQLite. https://requests-cache.readthedocs.io/en/stable/