If you're doing a single round-trip it's really not bad. You don't get that big an impact compared to the round-trip to the user.
If you are doing multiple dependent loads, e.g. loading an index that tells you which part of the data to load which tells you which other related table to look into (e.g. a complex join)... that would be bad.
If you are doing multiple dependent loads, e.g. loading an index that tells you which part of the data to load which tells you which other related table to look into (e.g. a complex join)... that would be bad.