From what I recall in the JRE and Sam Harris interviews, Jack seemed very reasonable. I think Twitter is something that's gotten away from him (certainly from what he'd like) and is being run by the inmates to a significant degree.
That was my impression as well. It was interesting to see Jack answer and then have the legal council (?) amend Jack's answers or push them in a specific direction. It's very clear that there is a mismatch between what Jack wants, what Twitter shareholders want, and what Twitter's activist pseudo-employee contingent wants.
Unsure if you’re asking who is running twitter or what’s meant by ‘inmates’ so will attempt to answer both.
I suspect it’s marketing people / short-sighted profit minded people rather than the legal team running the place.
And if you are asking about inmates meaning, it’s an idiom, “the inmates are running the asylum” meaning the least useful/knowledgeable people have taken over from the competent.