It looks like another addon was phoning home to a blocked resource. I should've tried more combinations first. The best thing I can think of is that it would be cool if uBlock reported when a call from another extension has been blocked.
> it would be cool if uBlock reported when a call from another extension has been blocked
That is the purpose of the built-in logger[1]. By default uBO is not setup to block other extensions' network requests, or those made by the browser itself, one has to configure it explicitly for this to happen[2].
That's bizarre! Have you tried disabling everything except uBlock and seeing if that persists? Maybe it's some kind of interaction with other addons causing the problem.
Another user recommended uMatrix as a Ghostery replacement in this thread which I was trying out, and it looks like some Ghostery/uBlock interaction was to blame. My best guess is some Ghostery resource is correctly flagged by uBlock and that the delay I experienced was a request timeout or similar, from Ghostery.
That makes sense, and oddly enough I was just (literally for the first time, 10 minutes ago) looking at switching out Ghostery for uMatrix. Decision made, thanks.