Indeed, at some point, you can't lower tail latencies any further without moving closer to your users. But of the 7 round trips that I mentioned above, you have control over 3 of them: 2 round trips can be eliminated by supporting HTTP/3 over QUIC (and adding HTTPS DNS records to your zone file), and 1 round trip can be eliminated by server-side rendering. That's a 40-50% reduction before you even need to consider a CDN setup, and depending on your business requirements, it may very well be enough.